News Summary
The New Orleans Saints will begin their NFL regular season on September 7, facing off against the Arizona Cardinals at the Caesars Superdome. With a six-game winning streak in season openers, the Saints aim to continue their success against a Cardinals team that historically leads the series. This highly anticipated matchup will be the Saints’ third season opener against the Cardinals. Fans are eager to see how the Saints will perform at home this year while navigating a challenging schedule featuring key matchups against notable teams.
New Orleans – The New Orleans Saints will kick off their 2025 NFL regular season on Sunday, September 7, against the Arizona Cardinals at Noon CT in the Caesars Superdome. The game marks an intriguing start for the Saints, who will seek to extend their current six-game winning streak in season openers, the longest active streak in the NFL.
The Cardinals have historically led the all-time regular season series against the Saints, holding a record of 16-15. However, New Orleans emerged victorious in their last meeting at the Superdome, winning convincingly 31-9 on October 27, 2019. The Saints have an impressive home record against the Cardinals, winning 8 of 12 matchups, including a notable 45-14 victory in the 2009 NFC Wild Card Playoff game.
This season opening against the Cardinals will be the third instance in franchise history, with the previous openers in 1982 and 2015 resulting in losses. As the Saints prepare for their home opener, they will look to continue their success at home, as this will be the third consecutive year they start the season in the Caesars Superdome.
The Saints’ schedule includes several key matchups throughout the season. Following their game against the Cardinals, they will host the San Francisco 49ers on September 14, also at Noon CT. The Saints have struggled historically against the 49ers, with the all-time series favoring San Francisco 49-27-2. Additionally, the Saints’ coaching staff has connections to the 49ers, as their defensive coordinator, Brandon Staley, served as assistant head coach of defense for San Francisco in 2024.
On September 28, the Saints will visit the Buffalo Bills, marking their sixth trip to Highmark Stadium, where they hold a 4-1 all-time record. The team will then welcome the New York Giants on October 5, where they are looking to capitalize on their two-game winning streak against New York.
The Saints face various teams that have had tough historical matchups against them, such as the New England Patriots, who lead the all-time series 10-6. However, New Orleans has bested the Patriots in their last two meetings. On October 19, they will square off against the Chicago Bears, against whom they have managed to win seven consecutive times, leading their all-time series 18-13.
The team’s divisional play begins on October 26 against the Tampa Bay Buccaneers, and New Orleans has the upper hand with a 40-26 lead in the all-time series. The season’s final game is set to be played in Atlanta, though the date is yet to be determined.
This year is particularly interesting as the Saints do not have any prime-time games on their schedule for the first time in 25 years, which may impact the visibility of the team this season. The strength of their schedule is rated at .419, marking it as the second easiest in the league.
Head Coach Kellen Moore will guide the Saints following the dismissal of Dennis Allen. A quarterback battle is anticipated between rookies Spencer Rattler and Tyler Shough, both of whom are expected to play significant roles as the team progresses through the season.
As for the preseason, the Saints are set to face the Los Angeles Chargers, Jacksonville Jaguars, and Denver Broncos, with the exact dates for some matchups still pending.
Fans are eager to see how the 2025 season unfolds as the Saints look to capitalize on their home-field advantage and add to their legacy within the league.
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Additional Resources
- Fox 8 Live: Saints Set to Open 2025 Season Home Against Cardinals
- New Orleans Saints Official Site: 2025 Schedule
- Arizona Sports: Cardinals 2025 Schedule
- ESPN: Saints 2025 Schedule Takeaways
- USA Today: How to Buy Saints Tickets
- Wikipedia: New Orleans Saints
- Google Search: New Orleans Saints 2025 Schedule
- Google Scholar: New Orleans Saints
- Encyclopedia Britannica: New Orleans Saints
- Google News: New Orleans Saints 2025
